Advice for healthcare professionals to provide to patients:

·         new measures are being introduced because there is evidence that taking topiramate during pregnancy can increase the risk to the baby of congenital malformation, low birth weight, intellectual disability, autistic spectrum disorder and attention deficit hyperactivity disorder

·         use effective birth control (contraception) at all times during your treatment with topiramate and for at least 4 weeks after the last dose

·         topiramate may interact with some hormonal contraceptives. Your General Practitioner (GP), specialist, sexual health and contraception clinic or contraception service in community pharmacy will discuss which method of birth control is best for you

·         if you are thinking about having a baby, make an appointment with your GP. Do not stop using topiramate and contraception before you have talked to your doctor

·         if you think you are pregnant and are taking topiramate for epilepsy, do not stop using topiramate. This may cause your seizures to start again or happen more often and last longer. Make an urgent appointment with your GP or epilepsy team (within a few days)

·         if you think you are pregnant and are taking topiramate for migraine prevention, stop taking topiramate straight away and contact your GP

·         it is important to visit your doctor to review your treatment at least once each year

·         always read the safety leaflet that comes with your medicine and consult the new Patient Guide for information about the risk of topiramate use during pregnancy